Mafatih al-Hayat is divided into five main parts and a sixth final part: The first part is on the interaction of humans with themselves. The chapters in this section include: thinking, learning, keeping the body clean, eat, dress, adornment, accommodation, travel, sleep, leisure, sports and so on. The second part, on interactions with others, has chapters on fellow Muslims, foreigners, the poor, enemies, citizens and so on. The third part is on the interaction between people and the Islamic regime, discussing political, social, municipal and economic affairs. The fourth part of Mafatih al-Hayat is on human interaction with animals and discusses taking care of animals, enjoying animals, animal rights, etc. The fifth part is about human interaction with the environment, including environmental issues, soil, trees, green space, wind, rain, rivers, roads, fuel, tourism and so on. The final part includes work on lunar months, traditions and so on.

Abdollah Javadi-Amoli is an Iranian Twelver Shi'a Marja. He is a conservative Iranian politician and one of the prominent Islamic scholars of the Hawza in Qom. The official website for his scientific foundation, Isra, describes him as a well-known, outstanding thinker in various fields of Islamic sciences and a distinguished figure in exegesis, jurisprudence, philosophy and mysticism. It is further states that his ideas and views have been reinforcing the Islamic Republic of Iran since the 1979 Islamic Revolution, and that "his strategic and enlightening guidance" has been "extremely constructive" during the past three decades.